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Catalog/Hormones/Female HRT
Hormones
THE STANDARD
S
FEMALE HRT
Estradiol + progesterone
BATCH 24-09-A1
Hormones

Female HRT.

Oral estradiol and micronized progesterone, prescribed together and compounded to your prescription. Estradiol treats the symptoms. Progesterone protects the lining of the uterus. Your doctor or clinician sets the starting strength, and adjusts it against your symptoms rather than a chart.

Choose your plan · all-in
Includes consultation · oral estradiol + progesterone · messaging · shipping

Payment is collected before clinical review. GEN displays the total due today at checkout. A licensed U.S. doctor or clinician then reviews your intake and decides whether to prescribe. A prescription is not guaranteed.

ClassEstradiol + micronized progesterone
CompoundC18H24O2 · C21H30O2
Mol. weight272.38 · 314.46 g/mol
Doctor- or clinician-approvedCompounded to orderThird-party testedMonthly plan · cancel anytime
All 50 states
Before you buy

Read this before you pay.

None of this is fine print. It is the arrangement, and we would rather you read it here than meet it at checkout.

  1. 01
    Why two hormones

    Estradiol is the one that treats the symptoms — hot flashes, night sweats, sleep that no longer holds, dryness. Progesterone is there for your uterus. Estrogen taken on its own thickens the lining of the uterus, and over time that raises the risk of endometrial cancer. Micronized progesterone keeps the lining in check. If you have a uterus, you take both. That is the protocol, not an add-on.

  2. 02
    What you bought

    A consultation, not a prescription. Your payment starts a review of your intake by a licensed U.S. doctor or clinician. If hormone therapy is right for you, they write the prescription in your name and the pharmacy compounds it to order. If it is not, they will tell you so. A prescription is not guaranteed, and we do not sell against medical judgment.

  3. 03
    What happens next

    The first weeks can bring bloating or breast tenderness while your body adjusts, and most of it settles. The full effect can take up to three months. Your doctor or clinician follows you through it and can change the dose at any point — up, down, or off. Monthly plan: cancel anytime.

  4. 04
    Still having periods?

    You can still qualify. Perimenopause — hot flashes, night sweats, or broken sleep that begin while your periods are still coming, however irregularly — is treated with these same two hormones. Tell your doctor or clinician where you are in the transition. It shapes the strength they choose.

  5. 05
    HSA / FSA eligible

    Prescribed hormone therapy is a qualified medical expense. HSA and FSA cards are accepted at checkout, or keep the itemized receipt and submit it for reimbursement.

  6. 06
    Compounded, not off the shelf

    Your estradiol and progesterone are prepared for your prescription by a licensed 503A or 503B compounding pharmacy. That makes them compounded medications, which are not FDA-approved: no compounded preparation is reviewed by FDA for safety or effectiveness before it is dispensed. It is why a doctor or clinician has to prescribe it, and why nothing here ships from stock.

What to expect

  1. Weeks 1–2

    Your body is adjusting. Some people notice quieter nights or fewer hot flashes. Many notice nothing yet — that’s normal.

  2. Weeks 3–6

    Sleep, mood, and vasomotor symptoms often start to shift. Your clinician may adjust dose based on how you respond.

  3. Months 2–3

    This is when fuller relief usually shows up, if HRT is the right fit for you. Results vary. A prescription is not guaranteed.

Chain of custody

Who handles your medication, at every step.

PRESCRIBED
Your doctor or clinician
DEA-registered · state-licensed
Issued at consult
COMPOUNDED
503A / 503B partner pharmacy
State-licensed facility
To your prescription
TESTED
Independent lab
Sterility · potency · endotoxin
Before release
RELEASED
Licensed pharmacist
Signs the batch record
Before shipping
Indications

Considered for adults with

  • Moderate to severe vasomotor symptoms of menopause — hot flashes, night sweats
  • Moderate to severe vulvar and vaginal atrophy due to menopause
  • Endometrial protection for anyone taking estrogen who still has a uterus
  • Prevention of postmenopausal osteoporosis, on doctor or clinician judgment
  • Perimenopause — the same symptoms while periods are still happening, on doctor or clinician judgment
Counter-indications

Not prescribed when

  • ×Known, suspected, or past breast cancer, or another estrogen-dependent cancer
  • ×Active or past blood clots — DVT, pulmonary embolism, stroke, or heart attack
  • ×Undiagnosed abnormal genital bleeding, or active liver disease
  • ×Pregnancy, planned pregnancy, or breastfeeding
© 2026 Clark Health Technologies, LLCThis site does not provide medical advice. A licensed doctor or clinician reviews every consultation.Made in the United States