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Catalog/Hormones/Female HRT
Hormones
FEMALE HRT
Estradiol + progesterone
Hormones

Female HRT.

Oral estradiol and micronized progesterone, prescribed together and compounded to your prescription. Estradiol is the main hormone in most HRT plans. Progesterone protects the lining of the uterus, so after a hysterectomy your clinician usually prescribes estradiol alone. Your clinician sets the strength and prescribes only if it’s appropriate for you.

Choose your plan · all-in
Includes consultation · oral estradiol + progesterone · messaging · shipping

Payment is collected before clinical review. GEN displays the total due today at checkout. A licensed U.S. doctor or clinician then reviews your intake and decides whether to prescribe. A prescription is not guaranteed.

Compounded drugs are not FDA-approved. FDA does not review compounded drugs for safety, effectiveness, or quality. Not a generic version of any brand-name drug. Rx only. A licensed clinician decides whether it’s appropriate for you.

ClassEstradiol + micronized progesterone
Prescribed only after clinician reviewCompounded for your prescriptionMonthly plan · cancel anytime
All 50 states and Washington, DC
Before you buy

Read this before you pay.

None of this is fine print. It is the arrangement, and we would rather you read it here than meet it at checkout.

  1. 01
    Why two hormones

    Estradiol is the main hormone in most HRT plans; your clinician decides the dose. Progesterone is there for your uterus. Estrogen taken on its own thickens the lining of the uterus, and over time that raises the risk of endometrial cancer. Micronized progesterone keeps the lining in check. If you have a uterus, you take both. That is the protocol, not an add-on. After a hysterectomy there is no lining to protect, so your clinician usually prescribes estradiol alone, on the same plan.

  2. 02
    What you bought

    A consultation, not a prescription. Your payment starts a review of your intake by a licensed U.S. doctor or clinician. If hormone therapy is right for you, they write the prescription in your name and the pharmacy compounds it to order. If it is not, they will tell you so. A prescription is not guaranteed, and we do not sell against medical judgment.

  3. 03
    What happens next

    The first weeks can bring bloating or breast tenderness while your body adjusts; tell your clinician about any side effect. Monthly plan: cancel anytime.

  4. 04
    Still having periods?

    You can still qualify. Perimenopause is a stage where your clinician may consider these same two hormones. Tell your doctor or clinician where you are in the transition. It shapes the strength they choose.

  5. 05
    HSA / FSA eligible

    Prescribed hormone therapy is a qualified medical expense. HSA and FSA cards are accepted at checkout, or keep the itemized receipt and submit it for reimbursement.

  6. 06
    Compounded, not off the shelf

    Your estradiol and progesterone are prepared for your prescription by a state-licensed 503A compounding pharmacy. That makes them compounded medications, which are not FDA-approved: FDA does not review compounded drugs for safety, effectiveness, or quality. Not a generic version of any brand-name drug. It is why a doctor or clinician has to prescribe it, and why nothing here ships from stock.

How it's filled

From prescription to your door.

PRESCRIBED
A licensed clinician
State-licensed
Only if appropriate
COMPOUNDED
State-licensed 503A pharmacy
On demand, for one prescription
After you are prescribed
DISPENSED
The compounding pharmacy
Labelled in your name
To your prescription
SHIPPED
To your door
Estimate begins after dispensing
Not from Buy Now
Eligibility

Who decides

Eligibility is determined by a licensed clinician based on your health history.

  • Moderate to severe vasomotor symptoms of menopause — hot flashes, night sweats
  • Moderate to severe vulvar and vaginal atrophy due to menopause
  • Endometrial protection for anyone taking estrogen who still has a uterus
  • Prevention of postmenopausal osteoporosis, on doctor or clinician judgment
  • Perimenopause — the same symptoms while periods are still happening, on doctor or clinician judgment
Counter-indications

Not prescribed when

  • ×Known, suspected, or past breast cancer, or another estrogen-dependent cancer
  • ×Active or past blood clots — DVT, pulmonary embolism, stroke, or heart attack
  • ×Undiagnosed abnormal genital bleeding, or active liver disease
  • ×Pregnancy, planned pregnancy, or breastfeeding
© 2026 Clark Health Technologies, LLCThis site does not provide medical advice. A licensed doctor or clinician reviews every consultation.Made in the United States

Compounded drugs are not FDA-approved. FDA does not review compounded drugs for safety, effectiveness, or quality. Not a generic version of any brand-name drug. Rx only. A licensed clinician decides whether it’s appropriate for you.

Available in all 50 states and Washington, DC.