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Catalog/Skin/Tretinoin Cream
Skin
TRETINOIN CREAM
30 g topical cream
Skin

Tretinoin Cream.

A prescription retinoid cream, applied at night as your clinician directs.

Prescription retinoid cream. Compounded to your prescription and applied at night. Stronger than over-the-counter retinol. Your clinician decides whether it’s appropriate for you, sets how often you start, and how you build.

$79 / month

Includes consultation · 30 g topical cream · refills to your prescription

Payment is collected before clinical review. GEN displays the total due today at checkout. A licensed clinician then reviews your consultation. A prescription is not guaranteed.

Compounded drugs are not FDA-approved. FDA does not review compounded drugs for safety, effectiveness, or quality. Not a generic version of any brand-name drug. Rx only. A licensed clinician decides whether it’s appropriate for you.

ClassAll-trans retinoic acid
RouteTopical · cream
Prescribed only after clinician reviewCompounded for your prescriptionCancel anytime
All 50 states and Washington, DC
Before you buy

Start slow. Use SPF.

Tretinoin can irritate skin at first. Start with the schedule your clinician gives you, tell them how your skin is tolerating it, and protect your skin from the sun every day.

  1. 01
    Nightly on clean, dry skin

    Start slow if your clinician says so — a few nights a week, then nightly.

  2. 02
    Expect an adjustment window

    Dryness, peeling, or redness for about 2–4 weeks is common. Moisturize. It usually settles.

  3. 03
    Daily broad-spectrum SPF is required

    Use it every day while using tretinoin.

  4. 04
    Not for pregnancy, trying to conceive, or breastfeeding

    Tell your clinician if any of these apply to you.

  5. 05
    Rx not guaranteed

    A licensed clinician reviews every consultation.

  6. 06
    Compounded to your prescription

    Pharmacy-dispensed as prescribed.

Pairs with: Copper peptide (GHK-Cu) is often used mornings or on off nights to support the barrier while adjusting to tretinoin — clinician-directed; do not layer at the same time.

What to expect

  1. Weeks 1–2

    Start on the schedule your clinician sets. Peeling or dryness is common. Tell your clinician if it doesn’t settle.

  2. Weeks 3–6

    Keep SPF and moisturizer. Your clinician sets how often you apply it.

  3. Months 2–3

    Keep the schedule your clinician set. Ask them before changing how often you apply it, or stopping.

How it's filled

From prescription to your door.

PRESCRIBED
A licensed clinician
State-licensed
Only if appropriate
COMPOUNDED
State-licensed 503A pharmacy
On demand, for one prescription
After you are prescribed
DISPENSED
The compounding pharmacy
Labelled in your name
To your prescription
SHIPPED
To your door
Estimate begins after dispensing
Not from Buy Now
Eligibility

Who decides

Eligibility is determined by a licensed clinician based on your health history.

  • Fine lines and other visible signs of photoaging, on clinician judgment
  • Uneven tone or rough texture
  • Acne-prone skin when prescription tretinoin is appropriate
  • Adults ready to use daily SPF and follow a clinician-directed adjustment schedule
Counter-indications

Not prescribed when

  • ×Pregnancy, trying to conceive, or breastfeeding
  • ×Known sensitivity to tretinoin or another ingredient in the prescribed preparation
  • ×Sunburned, broken, eczematous, or actively irritated skin at the application site
  • ×Another prescription topical on the same area, unless your clinician has cleared both
© 2026 Clark Health Technologies, LLCThis site does not provide medical advice. A licensed doctor or clinician reviews every consultation.Made in the United States

Compounded drugs are not FDA-approved. FDA does not review compounded drugs for safety, effectiveness, or quality. Not a generic version of any brand-name drug. Rx only. A licensed clinician decides whether it’s appropriate for you.

Available in all 50 states and Washington, DC.